Free radicals: their beneficial and detrimental effects on sperm function.

نویسندگان

  • Shiva Kothari
  • Aaron Thompson
  • Ashok Agarwal
  • Stefan S du Plessis
چکیده

Free radicals are molecules with one or more unpaired electron(s) commonly found in seminal plasma. Physiologically, free radicals control sperm maturation, capacitation and hyperactivation, the acrosome reaction, and sperm-oocyte fusion. Pathologically, free radicals induce lipid peroxidation, DNA damage and apoptosis of spermatozoa. The present review deals with both the beneficial and detrimental effects of free radicals on sperm function.

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عنوان ژورنال:
  • Indian journal of experimental biology

دوره 48 5  شماره 

صفحات  -

تاریخ انتشار 2010